Biochemical Engineer

PsiOxus Therapeutics Ltd is an award winning Oxford based development stage biotechnology company developing novel therapeutics for the treatment of cancer, with a focus on immunotherapeutic approaches.  We have a first- generation oncolytic virus in Phase I/II clinical development and are developing an innovative pipeline of clinical, pre-clinical and research candidates using our proprietary T-SIGn cancer gene therapy platform technology. 


The Company is at an exciting stage of development recently rated number 25 in The Sunday Times Hiscox Top Tech Track, and recognised in FierceBiotech’s 2017 Fierce 15 as one of only two European countries listed, and the only one in the UK.  We have also been awarded at the Best Established Biotech at the 2017 OBN awards. Our headcount nearly doubled in 2017 and is set to grow substantially in 2018, offering significant future career opportunities for the right person.


The Role

Reporting directly to the Head of MS&T this is an exciting newly created opportunity to join the team, taking the lead in defining and conducting the lab and plant work necessary to develop, optimise and scale up the associated upstream and downstream processing.  The core function of the role is to lead and provide technical expertise on all aspects of process engineering.  The work will involve hands-on evaluation of process options and development/optimisation of processes in the laboratory and the transfer of lab-scale processes to pilot plant and beyond. The role may entail supervision of more junior scientists and close liaison with others within the team responsible for development and scale-up of the bioreactor process.


We are looking for someone that has several years hands-on industrial experience in the development of downstream processing of microbial biomass for recovery of recombinant proteins and transfer of these processes to plant scale.  In addition you will also have the following attributes:


  • Proven ability to work and communicate effectively as part of a team and internal/external stakeholders.

  • Excellent attention to detail.

  • Good organisational skills.

  • Experience in manufacturing in a GMP environment would be advantageous.

  • Applicants must be self-motivated, work to tight deadlines and be capable of readily adapting to changing priorities in a fast-paced environment.


In return we offer an attractive remuneration package including salary, pension, private healthcare and other benefits.  To apply please click on the Apply button to upload your CV and covering letter.


The closing date for applications is 31 August 2018, however applications will be evaluated in the order that they are received. You are therefore encouraged to apply as soon as possible.