Project Manager (CMC)

PsiOxus Therapeutics Ltd is an Oxford based development stage biotechnology company developing novel therapeutics for the treatment of cancer, with a focus on immunotherapeutic approaches.  We have a first- generation oncolytic virus in Phase I/II clinical development and are developing an innovative pipeline of clinical, pre-clinical and research candidates using our proprietary T-SIGn cancer gene therapy platform technology.

We have an exciting opportunity for an experienced Project Manager to join our Chemistry, Manufacturing and Control (CMC) team at our Abingdon, Oxfordshire facility. This position will take responsibility for the delivery of our project outcomes through key development milestones with emphasis on CMC related project activities and outcomes.

Coming from a biopharmaceutical background we are looking for candidates that have worked on projects outside of scientific competence and that have contributed to the success of projects by facilitating the work of others as opposed to providing solutions themselves. You will have held budgetary responsibility for the delivery of projects, and experience with capital projects of up to £10million is preferred.


Key responsibilities include but are not limited to:

  • Direct, plan, manage and drive implementation for CMC projects from candidate selection through key milestones. Direct cross-functional matrix project teams comprising of internal and external members, in setting and agreeing roles and responsibilities.

  • Develop update and manage project plans timelines to achieve project objectives in line with corporate needs.

  • Manage project risks and issues; and capture any scope changes to the project in contract amendments.

  • Interface, influence and communicate with key stakeholders and governance committees to ensure project visibility and timely decisions.

  • Chair project team meetings — ensure the conduct of efficient team meetings - maintain action lists, risk logs etc., circulate agendas / minutes, perform risk management, contingency planning and scenario modelling activities as required.

  • Ensure learning, transfer and utilisation of project management and drug development best practices across projects.

  • Provide accurate and complete project information, including regular updates as required.

  • Ensure that appropriate members of the team and/or external experts scientifically review all deliverables required for product development.

  • Manage the timely preparation of high quality internal/external documentation used for project reviews and/or regulatory interactions.


Technical Experience

We are looking for candidates that have a minimum of 5 years’ project management/project leadership experience reflecting a track record of project delivery generating significant value to an industrial organisation in the pharmaceutical or biotechnology field.

Specific expertise in CMC activities (including the development of virology, vaccines, or oncology products) is required. In addition, direct project management and experience of early stage Phase I/II oncolytic virus and vaccine clinical trials will be highly advantageous.

Excellent project management skills - good working knowledge of project management software including MS Project and Excel is essential.

Appropriate Project Management qualifications (PMP preferred) are desirable, but not essential. 


Personal Abilities and Traits

 The successful candidate will:

  • have personal credibility - personal impact, knowledge, ability to understand and respond to project and business requirements, ability to challenge as appropriate without causing undue confrontation; 

    take accountability: - "can do" attitude with strong focus and commitment to delivering;

  • take action: - able to represent different functional areas on behalf of PsiOxus when interacting with other external stakeholders:

  • have personal integrity and professionalism; open and straight forward style;

  • have excellent interpersonal skills - strong cross-functional influencing, negotiating and team working skills. A collaborative manner is essential; and

  • be a highly effective communicator, both orally and in writing.

The Company is at an exciting stage of development recently rated number 25 in The Sunday Times Hiscox Top Tech Track, and recognised in FierceBiotech’s 2017 Fierce 15 as one of only two European countries listed, and the only one in the UK. We have also been awarded at the Best Established Biotech at the 2017 OBN awards. Our headcount nearly doubled in 2017 and is set to grow substantially in 2018, offering significant future career opportunities for the right person.

The closing date is Friday 30 March 2018 however applications will be evaluated in the order that they are received, and you are therefore encouraged to apply as soon as possible.